Alec Brundle, Nanea K. Perkins, Mackenzie J. Perpetua, Natalie C. Stagnitti and Emily J. Schafer

Abstract:

Apios americana is a plant that was traditionally used as a food-source by indigenous North Americans. Previous research has identified several secondary metabolites along with the nutrient content of this crop plant, but further research is warranted due to its outstanding health benefits, medicinal properties, and its potential for use in cosmetics. Chemical investigation, including 1D and 2D NMR spectra, of the non-polar extract of A. americana tubers found the first evidence of lupeol esters in this plant. Lupeol esters are known to have several beneficial effects including anti-inflammatory, anticancer, and skin-cell regrowth activities. Further data provided evidence that of the lupeol esters present, lupeol cinnamate and lupeol acetate are the most abundant.